Search Results for: antioxidant

NADPH, a directly operating antioxidant ABSTRACT Endogenous oxygen- and nitrogen-centered free radicals are considered to play a decisive role in a variety of diseases such as neurodegenerative disorders, atherosclerosis, or cancer. Directly operating antioxidants limit the action of freely diffusing radicals by scavenging the attacking, oxidizing radical and rereducing the oxidized biomolecule, i.e., the biomolecule-…

NAD(P)H a directly operating antioxidant

Age Related Changes in NAD+ Metabolism Oxidative Stress Introduction Multiple degenerative processes are implicated in natural senescence. As aging is associated with progressive decline in organ function, elucidating the complex pathways controlling the rate of aging is of significant clinical importance [1]. An important mechanism contributing to aging is oxidative stress. The ‘‘freeradical theory of…