NAD and NADH in Neuronal Death

NAD and NADH in Neuronal Death

Abstract Neuronal death is a key pathological event in
multiple neurological diseases. Increasing evidence has
suggested that NAD+ and NADH mediate not only energy
metabolism and mitochondrial functions, but also calcium
homeostasis, aging, and cell death. This article is written to
provide an overview about the information suggesting
significant roles of NAD+ and NADH in neuronal death
in certain neurological diseases. Our latest studies have
suggested that intranasal administration with NAD+ can
profoundly decrease ischemic brain damage. These observations
suggest that NAD+ administration may be a novel
therapeutic strategy for some neurological diseases…

nadhwiki has written 69 articles

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