In Vivo Analysis of the Mechanisms for Oxidation of Cytosolic NADH
In Vivo Analysis of the Mechanisms for Oxidation of Cytosolic NADH During respiratory glucose dissimilation, eukaryotes produce cytosolic NADH via glycolysis. This NADH has to be reoxidized outside the mitochondria, because the mitochondrial inner membrane is impermeable to NADH. In Saccharomyces cerevisiae, this may involve external NADH dehydrogenases (Nde1p or Nde2p) and/or a glycerol-3-phosphate shuttle…